| Name | Goals | Yellow | Red | Team | ||
|---|---|---|---|---|---|---|
| 1. | Eto\'o | 114 | 1 | 0 | Bolton Wanderers | |
| 2. | | Ronaldo | 52 | 0 | 0 | Chelsea |
| 3. | | Messi | 49 | 0 | 0 | Manchester United |
| 4. | | Robinho | 43 | 3 | 0 | Manchester City |
| 5. | | Carew | 42 | 0 | 0 | West Bromwich |
| 6. | | Lennon | 39 | 1 | 0 | Stoke City |
| 7. | | Defoe | 34 | 0 | 0 | Portsmouth |
| 8. | | Henri Camara | 33 | 0 | 0 | Wigan Athletic |
| 9. | | Trezeguet | 28 | 0 | 0 | West Ham United |
| | Kamara | 28 | 0 | 0 | Liverpool | |